Iyini i-Frankincense Extract?
I-Frankincense extract iyingxenye esebenzayo egxilile etholakala ku-resin yezihlahla ze-Boswellia serrata, ngokuyinhloko equkethe i-pentacyclic triterpenoids eyingqayizivele. Isebenzisa ubuchwepheshe besimanje bokukhipha i-CO₂, igcina{1}izakhi ezilwa nokuvuvukala eziyigugu ukuze kutholwe ukukhishwa okujwayelekile. Leli khambi lasendulo elaziwa ngokuthi "igolide eliwuketshezi" manje selivela kabusha ekwakhiweni kwesayensi.
Izingxenye Ezibalulekile Ze-Bioactive Nezindlela
I-Boswelic Acids
Ivimbela ngokukhethekile i-5-lipoxygenase (5-LOX)
Ivimba i-leukotriene synthesis (85-90% inhibition)
Ivimbela ngokukhethekile i-MMP-3/9 matrix metalloproteinase
I-AKBA (Acetyl-11-keto- -boswellic acid)
Ingxenye enamandla kakhulu elwa{{0}nokuvuvukala{0}(3-5x kunamandla)
Yehlisa i-NF-κB indlela
Icindezela isisho se-COX-2
Ama-Polyterpenoids
Ithuthukisa ukwanda kwe-chondrocyte (ukwanda kwe-30-40%)
Ivuselela ukwakheka kwe-collagen
Ilungisa ibhalansi ye-immune cytokine
Izinzuzo Ezifakazelwe Ngokomtholampilo
Ukuphathwa Kokuvuvukala Okuhlangene
50-60% ukuthuthukiswa kwezikolo ze-WOMAC
40% isikhathi sokuxazulula ukuvuvukala esifushane
Ukwehliswa kwe-65% ekusetshenzisweni kwama-NSAID
Ukunciphisa Ukuvuvukala Kwamathumbu
I-55-70% yokunciphisa inkomba ye-DAI ezigulini ze-UC
2-3x ngokushesha ukulungiswa kwe-mucosal
Ilawula amaprotheni ahlanganayo aqinile
I-Respiratory Anti{0}}ukuvuvukala
15-25% ukuthuthukiswa kwe-FEV1 ku-asthma
Yehlisa i-hyperreactivity ye-bronchial
Ivimbela i-mucus hypersecretion
Imihlahlandlela yokusebenzisa
Umthamo: 300-600mg/day (30-40% boswellic acids)
Inhlanganisela engcono kakhulu: 1: 1 ne-curcumin
Isifundo: Imiphumela ebalulekile ngemva kwamasonto angu-8-12
Izinyathelo zokuzivikela
▲ Isexwayiso ngesikhathi sokukhulelwa/ukuncelisa
▲ Ingase ibe namandla ama-anticoagulants
▲ Thatha kanye nokudla kweziguli zezilonda
Izinkomba Zekhwalithi
① Okuqukethwe okumisiwe (AKBA Inkulu noma ilingana no-5%)
② Ukukhishwa{0}}okugcwele kwe-spectrum
③ Ukuthuthukiswa kwe-Bioavailability
Ubufakazi bomsebenzisi
"Ngemuva kwezinyanga ezi-3, ishumi leminyaka lami{1}}ubuhlungu be-lumbar behla ngo-70%" - 45isisebenzi sasehhovisi se-yo
"Isikhathi sokuphinda kwe-UC sinwetshwa ngezinyanga ezingu-6" - 38isiguli se-IBD
