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Incazelo Yomkhiqizo

Ukukhishwa kwembewu ye-Cassia kuyinhlanganisela ye-bioactive egxilile etholakala ngezindlela zesimanje zokukhipha (isb., i-CO₂ ebaluleke kakhulu,{2}}i-homogenization ephezulu, i-ethanol extraction). Ngokwesiko esetshenziswa imithi Chinese forisibindi detoxification, umbono ngcono, futhi laxative imiphumela, ucwaningo lwesimanje luqinisekisa ukusebenza kwayo kuukunciphisa i-lipid, ukulawula i-uric acid, nomsebenzi we-antioxidant.

Imininingwane Yezobuchwepheshe

1.Izindlela Zokukhipha

Izindlela Ezivamile

I-Decoction yamanzi: Ilula kodwa ingasebenzi kahle, ifanele izinto{0}}ezincibilikayo kuphela.

Ukukhishwa kwe-Ethanol:

Isebenzisa76-95% i-ethanolngokushisa okuphindaphindiwe kwe-reflux (imijikelezo engu-3 × amahora angu-3) ukuthuthukisa isivuno se-anthraquinone.

Ilungele i-lipid-inhlanganisela encibilikayo (isb, ama-cassiasides).

I-Advanced Extraction Technologies

I-Supercritical CO₂ Extraction:

Izimo: 25–35 MPa, 45–55℃, 60–120 min; ihlukanisa amafutha anamafutha ngenkathi ilondoloza ukushisa-izingxenye ezizwelayo.

Kuhlanganiswe neukucindezela okuphezulu{{0}okuphansi{1}}okuphansi okuqhubekayo kokukhipha (25–35 MPa, 25–35°C) to boost flavonoid/polysaccharide yields (>65%).

-I-Pressure Homogenization (HPH):

Ingcindezi engu-200–400 MPa iphazamisa izindonga zamaseli ngokusebenzisa amandla e-cavitation/shear, ikhulisa isivuno se-polysaccharide ngo-50% uma kuqhathaniswa nezindlela zendabuko.

Ukucubungula{0}}kwezinga lokushisa eliphansi (<40°C) prevents thermal degradation.

I-Ultrasound-I-Assisted Extraction (UAE):

Kumataniswe neama-deep eutectic solvents (DES)(isb, i-choline chloride-i-ethylene glycol); elungiselelwe ku-480 W, 61℃, 60 min, ukuzuza isivuno se-polysaccharide engu-15.89%.

Ukuhlanzwa & Ukugxila

I-Macroporous Resin Adsorption: Inothisa i-anthraquinone (kufika ku-4% inani lokuqukethwe).

Reverse Osmosis Membrane Concentration: Yehlisa izinsalela ze-solvent, ithuthukisa ubumsulwa.

2.Ukulawulwa Kwekhwalithi

Izindlela Zokuhlaziya:

I-HPLC: Ilinganisa i-chrysophanol, i-obtusin, njll.

I-UPLC{{0}Q-TOF/MS: Ucwaningo lwe-Metabolomics (isb, i-uric acid{2}}izindlela zokwehlisa).

Imininingwane: Isamba se-anthraquinones 0.5–4%, amanzi{2}}impushana encibilikayo (4:1 noma 10:1 concentrate).

Izinzuzo Zomkhiqizo

I-Bioactivity ephezulu:

Ukwehliswa kwe-lipid-: Ivimbela ukumuncwa kwe-cholesterol (isb, i-Shanzha lipid-amaphilisi okwehlisa ane-cassia/hawthorn synergy).

Ukunciphisa i-Uric acid: Ukukhipha okunamanzi kushintsha ama-metabolites omchamo ukuze kwehle i-uric acid.

I-Antioxidant: Ama-Flavonoid akhipha ama-radicals mahhala, avikela ama-hepatocyte (agunyazwe kumamodeli we-HepG2).

Ukuphepha: Kuqashelwa njengokudla-ukusetshenziswa komuthi okumbaxambili{1}}okunemiphumela engemihle emincane (isilinganiso se-anthraquinone siyalawulwa).

Ukucubungula Okusha: I-HPH kanye ne-CO₂ ebaluleke kakhulu yandisa isivuno futhi ilondoloze okusebenzayo.

Izinhlelo zokusebenza

Ezemithi:

Izidakamizwa zokwehlisa i-lipid-(isb., amaphilisi embewu ye-cassia ehlanganisiwe).

I-Uric acid-eyehlisa ukwakheka (okukhishwe okunamanzi okunegunya lobunikazi).

I-Nutraceuticals:

Ukulawulwa kwesisindo (umphumela we-laxative), inhlanganisela yezempilo yamehlo (ne-lutein).

Izimonyo:

Ukulawulwa-kawoyela kanye{1}}nemikhiqizo elwa nezinduna (i-sebum inhibition).

Izithasiselo Zokudla Kwezilwane: Ithuthukisa ukungatheleleki.

Ukupakisha & Isitoreji

Ukupakisha: 1kg/isikhwama se-foil, 25kg/fiber drum (customizable)
Isitoreji: Gcina endaweni epholile, eyomile, evaliwe futhi evikelekile ekukhanyeni
Impilo yeshelufu: izinyanga ezingama-24 (ngaphansi kwezimo ezingavulwa)

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